# Aptevo Therapeutics (APVO) — Overview

APVO · NASDAQ · Stock

Canonical page: https://www.lighthorse.io/tickers/apvo

## Price

Last close $1.70 on Oct 15, 2026. 52-week range $1.70 – $29.34.

## Company profile

Aptevo Therapeutics Inc is a clinical-stage research and development biotechnology company focused on developing novel immunotherapeutic candidates for the treatment of different forms of cancer. Its clinical candidates are; ALG.APV-527, which targets co-stimulatory receptors and tumor antigens, and CD3xCD123, which is being developed as a potential treatment of frontline acute myelogenous leukemia. The company's preclinical candidates, APVO711, CD3xCD123, APVO0442, and APVO603, are being developed using the ADAPTIR modular protein technology platform. The company's versatile and robust ADAPTIR and ADAPTIR-FLEX platforms are designed to generate monospecific, bispecific, and multi-specific antibody candidates that are capable of enhancing the human immune system against cancer cells.

## Financials

| Metric | Value |
| --- | --- |
| Revenue (trailing twelve months) | $0.00 |
| Revenue (quarter) | $0.00 |
| Revenue growth (year over year) | 0.00% |
| Gross profit (trailing twelve months) | $0.00 |
| Gross margin | 0.00% |
| Net income (trailing twelve months) | $0.00 |
| Net income (quarter) | −$6.4M |
| Net income growth (year over year) | -2.45% |
| Net margin | 0.00% |
| Return on equity | -446.89% |
| EPS (trailing twelve months) | $456.62 |
| Book value per share | $4.26 |
| P/E (trailing twelve months) | — |
| Price to book | 0.5 |
| Debt to assets | 58.39% |
| Payout ratio | 0.00% |
| Dividend yield | 0.00% |

## Frequently Asked Questions

### How do I buy stock in Aptevo Therapeutics (APVO)?

APVO trades commission-free with a Light Horse Securities brokerage account — from the mobile app, the web at [Light Horse Dashboard](https://portal.lighthorse.io), the trading API, or an [AI agent connected over MCP](/instructions/ai/claude). The trade panel on this page places the order once you are signed in.

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