# Lyell Immunopharma (LYEL) — Overview

LYEL · NASDAQ · Stock

Canonical page: https://www.lighthorse.io/tickers/lyel

## Price

Last close $8.19 on Oct 15, 2026. 52-week range $7.51 – $38.60.

## Company profile

Lyell Immunopharma Inc s a late-stage clinical cell therapy company advancing a pipeline of proprietary next-generation autologous chimeric antigen receptor (CAR) T-cell product candidates for patients with hematologic malignancies and solid tumors. The Company's product candidate, rondecabtagene autoleucel (ronde-cel, also known as LYL314), is an autologous dual-targeting CD19/CD20 CAR T-cell therapy in development for large B-cell lymphoma (LBCL). The Company has recently acquired exclusive rights outside of mainland China, Hong Kong, Macau and Taiwan, to a novel guanylyl cyclase C (GCC)-targeted CAR T-cell product candidate in early clinical development for refractory metastatic colorectal cancer (mCRC) and other GCC-expressing cancers.

## Financials

| Metric | Value |
| --- | --- |
| Revenue (trailing twelve months) | $27,000.00 |
| Revenue (quarter) | $4,000.00 |
| Revenue growth (year over year) | -50.00% |
| Gross profit (trailing twelve months) | $27,000.00 |
| Gross margin | 100.00% |
| Net income (trailing twelve months) | −$248.5M |
| Net income (quarter) | −$44.8M |
| Net income growth (year over year) | -4.85% |
| Net margin | -920285.19% |
| Return on equity | -93.28% |
| EPS (trailing twelve months) | −$12.69 |
| Book value per share | $9.99 |
| P/E (trailing twelve months) | — |
| Price to book | 0.9 |
| Debt to assets | 24.86% |
| Payout ratio | 0.00% |
| Dividend yield | 0.00% |

## Frequently Asked Questions

### Is Lyell Immunopharma (LYEL) profitable?

No. Lyell Immunopharma reported a net loss of $248.5M over the trailing twelve months.

### How much revenue does Lyell Immunopharma (LYEL) make?

Lyell Immunopharma generated $27,000.00 in revenue over the trailing twelve months, down 50.00% year over year.

### How do I buy stock in Lyell Immunopharma (LYEL)?

LYEL trades commission-free with a Light Horse Securities brokerage account — from the mobile app, the web at [Light Horse Dashboard](https://portal.lighthorse.io), the trading API, or an [AI agent connected over MCP](/instructions/ai/claude). The trade panel on this page places the order once you are signed in.

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Data provided by [AInvest](https://www.ainvest.com).