# Protagonist (PTGX) — Overview

PTGX · NASDAQ · Stock

Canonical page: https://www.lighthorse.io/tickers/ptgx

## Price

Last close $136.55 on Oct 15, 2026. 52-week range $73.50 – $158.62.

## Company profile

Protagonist Therapeutics Inc is a biopharmaceutical company engaged in the discovery and development of peptide-based therapeutics using its proprietary technology platform. The company focuses on three therapeutic areas: inflammation and immunology, hematology, and metabolic diseases. Its pipeline includes clinical-stage and preclinical candidates such as rusfertide for polycythemia vera, icotrokinra for inflammatory diseases, and other programs targeting IL-17, obesity, and iron metabolism disorders, developed through internal research and strategic collaborations.

## Financials

| Metric | Value |
| --- | --- |
| Revenue (trailing twelve months) | $282.0M |
| Revenue (quarter) | $213.5M |
| Revenue growth (year over year) | 3749.17% |
| Gross profit (trailing twelve months) | $282.0M |
| Gross margin | 100.00% |
| Net income (trailing twelve months) | $82.9M |
| Net income (quarter) | $162.8M |
| Net income growth (year over year) | 568.35% |
| Net margin | 29.40% |
| Return on equity | 10.98% |
| EPS (trailing twelve months) | $1.22 |
| Book value per share | $13.01 |
| P/E (trailing twelve months) | 106.6 |
| Price to book | 10.5 |
| Debt to assets | 4.97% |
| Payout ratio | 0.00% |
| Dividend yield | 0.00% |

## Frequently Asked Questions

### Is Protagonist (PTGX) profitable?

Yes. Protagonist earned $82.9M in net income over the trailing twelve months, a net margin of 29.40%.

### How much revenue does Protagonist (PTGX) make?

Protagonist generated $282.0M in revenue over the trailing twelve months, up 3749.17% year over year.

### What is PTGX's P/E ratio?

Protagonist trades at 106.6 times trailing twelve-month earnings, on an EPS of $1.22.

### How do I buy stock in Protagonist (PTGX)?

PTGX trades commission-free with a Light Horse Securities brokerage account — from the mobile app, the web at [Light Horse Dashboard](https://portal.lighthorse.io), the trading API, or an [AI agent connected over MCP](/instructions/ai/claude). The trade panel on this page places the order once you are signed in.

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Data provided by [AInvest](https://www.ainvest.com).