# Silence Therapeutics (SLN) — Overview

SLN · NASDAQ · Stock

Canonical page: https://www.lighthorse.io/tickers/sln

## Price

Last close $9.35 on Oct 15, 2026. 52-week range $4.30 – $15.43.

## Company profile

Silence Therapeutics PLC is a biotechnology company focused on discovering and developing novel molecules incorporating short-interfering ribonucleic acid or siRNA. Using its mRNAi GOLD platform, the company has generated siRNA product candidates both for its internal development pipeline as well as for out-licensed programs with third-party collaborators. Its wholly owned pipeline is focused on three therapeutic areas: cardiovascular disease, hematology, and rare diseases. The different product candidates in its pipeline are Divesiran (SLN124), a siRNA product candidate that has the potential to treat several hematological disorders; Zerlasiran (SLN360), being developed as a potential treatment to reduce cardiovascular issues; SLN-312; SLN-548; and multiple other programs.

## Financials

| Metric | Value |
| --- | --- |
| Revenue (trailing twelve months) | $615,000.00 |
| Revenue (quarter) | $0.00 |
| Revenue growth (year over year) | 0.00% |
| Gross profit (trailing twelve months) | $528,000.00 |
| Gross margin | 85.85% |
| Net income (trailing twelve months) | −$60.0M |
| Net income (quarter) | −$12.3M |
| Net income growth (year over year) | 55.15% |
| Net margin | -9748.46% |
| Return on equity | -90.41% |
| EPS (trailing twelve months) | −$1.29 |
| Book value per share | $0.81 |
| P/E (trailing twelve months) | — |
| Price to book | 14.6 |
| Debt to assets | 63.85% |
| Payout ratio | 0.00% |
| Dividend yield | 0.00% |

## Frequently Asked Questions

### Is Silence Therapeutics (SLN) profitable?

No. Silence Therapeutics reported a net loss of $60.0M over the trailing twelve months.

### How much revenue does Silence Therapeutics (SLN) make?

Silence Therapeutics generated $615,000.00 in revenue over the trailing twelve months.

### How do I buy stock in Silence Therapeutics (SLN)?

SLN trades commission-free with a Light Horse Securities brokerage account — from the mobile app, the web at [Light Horse Dashboard](https://portal.lighthorse.io), the trading API, or an [AI agent connected over MCP](/instructions/ai/claude). The trade panel on this page places the order once you are signed in.

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Data provided by [AInvest](https://www.ainvest.com).