Septerna (SEPN) earnings history
Most recent quarter
- Fiscal period
- Q3 2025
- Period end
- Sep 30, 2025
- EPS actual
- $0.18
- EPS estimate
- $0.12
- EPS surprise
- +45.99%
- Revenue surprise
- −76.55%
- Revenue
- $21.5M
- Revenue estimate
- $91.7M
- Reported
- Nov 10, 2025
Septerna's latest quarter in the table is Q3 2025, reported on November 10, 2025. Earnings were $0.18 per share, beating the $0.12 estimate by 45.99%. Revenue was $21.5 million, 76.55% below the $91.7 million consensus. The table has no Q3 2024 figures, so there is no year-earlier comparison.
The record is short, with three quarters: Q4 2024, Q1 2025 and Q3 2025. Q2 2025 is not in the table. The two earlier quarters were losses, of $0.64 and $0.49 per share, on revenue of about $0.2 million each. Q3 2025 was the first profit shown, and its revenue was about 98 times the Q1 level. Septerna beat EPS estimates twice and missed once, and topped revenue estimates in the first two quarters before the large Q3 shortfall.
The table holds no quarters after Q3 2025. The only fourth-quarter report shown came on March 27, 2025, and the Q3 2025 report came 41 days after the quarter closed. Newer results will extend this record when they are added, giving the first year-over-year comparisons for the company.
Earnings history
Quarterly revenue
Frequently asked questions
When did Septerna (SEPN) last report earnings?
Septerna last reported on Nov 10, 2025, covering fiscal Q3 2025.
Did SEPN beat earnings estimates?
Yes. Septerna reported EPS of $0.18 for Q3 2025 against a $0.12 estimate — a 45.99% beat.
How much revenue did SEPN report last quarter?
Septerna reported $21.5M in revenue for Q3 2025, against a consensus estimate of $91.7M.
Earnings figures may be restated, revised or corrected by the issuer. Past results do not indicate future performance.
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